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High-level disinfection (HLD) can be achieved with a manual or automated process. A manual HLD process typically involves soaking a device for some time within a specific temperature and concentration. For most endoscopes, industry standards/guidelines recommend that automated endoscope reprocessors be used to provide a more efficient, consistent, and measurable outcome. STERIS offers HLD chemistry products for manual soaking, and some of these have also been validated for use in an AER system.